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Researchers at Arc Institute have discovered a completely new molecular system for editing DNA using RNA. The system enables programmable DNA changes such as inserting, removing or inverting DNA sequences.
- Researchers at Arc Institute have discovered a completely new molecular system for editing DNA using RNA.
- The system enables programmable DNA changes such as inserting, removing or inverting DNA sequences.
- The technique could potentially solve some of the biggest challenges with current gene editing methods.
A new tool for genome design
Researchers at Arc Institute haveĀ discoveredĀ a new molecular system that makes it possible to program DNA changes using RNA. The system, called “bridge RNA”, is the first natural RNA-guided recombination system that can insert, remove or invert any DNA sequences of choice.
The discovery, published in the journal Nature, was made by researchers at Arc Institute in collaboration with the University of California, Berkeley and the University of Tokyo. The system originates from so-called IS110 elements, a type of “jumping genes” that can move themselves within and between microbial genomes.
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