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COVID-19 Trial Indicates Symptoms Don’t Impact Transmission

By Zachary Stieber

The COVID-19 clinical trial where scientists purposefully infected volunteers showed that the symptoms an infected person experienced did not indicate how likely they were to pass on the virus that causes COVID-19, researchers behind the trial said.

“There was no correlation between the amount of viral shedding by qPCR or FFA and symptom score,” researchers with Imperial College in London said in a paper published by Nature Medicine expanding on the findings.

Some key findings from the trial were announced in February.

FFA stands for focus-forming assay, or a way to quantify viruses like SARS-CoV-2; qPCR refers to quantitative polymerase chain reaction testing. Both were used to test viral load, the amount of virus present in an individual that could lead to transmission…

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