Children's Health Defense Researchers at Rice University found that CRISPR-induced double-strand breaks in the DNA caused numerous large unintended on-target genetic damages, including large and small deletions and insertions and chromosomal rearrangements of genetic material.
The latest in a long series of papers has been published, detailing the unintended effects of CRISPR gene editing. The new review summarises the many types of serious unintended on-target (at the intended edit site) DNA damage resulting from CRISPR/Cas gene editing.
The review appears as the European Commission and the U.K. government maintain their pretense that gene editing is a precise, predictable and controllable technique and that food plants made with this technology are therefore as safe as those produced by conventional breeding.
The authors of the new paper, from Rice University in the U.S., reviewed the literature on CRISPR gene editing in human, primate and mouse cells.
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