The Israeli authors of a peer-reviewed study published this month in Pediatric Rheumatology said their findings warrant further research to understand the long-term effects of COVID-19 vaccines in children.
Children and adolescents who received at least one COVID-19 vaccine had a 23% higher risk of developing autoimmune disease compared to unvaccinated children, according to the findings of a peer-reviewed study published last week in Pediatric Rheumatology.
Growing “concerns about the emergence of new autoimmune diseases” prompted the study, according to the four Israeli researchers who authored the paper.
Using the health records of 493,705 Israeli patients up to age 21, the authors studied the incidence of autoimmune diseases, which occur when the immune system attacks the body instead of defending it, in vaccinated and unvaccinated subjects before and during the COVID-19 pandemic.
The study measured a hazard ratio of 1.2323 for patients who received at least one dose of a COVID-19 vaccine. This translates to a 23.2% greater risk of developing an autoimmune disease when controlling for age, sex and socioeconomic status — a statistically significant outcome, according to the study.
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