
A clinical trial has demonstrated adults with peanut allergies may be able to eat small doses if they undergo fecal transplants, a hospital announced Saturday.
Fecal microbiota transplanted out of nonallergic donors into allergic people who previously could only eat less than half a peanut before reacting resulted in adults who became resilient to two peanuts, Boston Children’s Hospital said.
“These results were very encouraging,” said Dr. Rima Rachid, the lead investigator and co-director of the Food Allergy Program at the hospital. “A single FMT led to a significant increase in the threshold of reactivity to peanut at both 1 month and 4 months after treatment, showing that the effect was prolonged. This study is offering hope that microbiome interventions may be effective in food allergy.”