Scientists have uncovered a hidden class of RNA structures deep inside the human microbiome, completely unlike anything seen before.
A newly identified class of RNA molecules has been discovered in bacteria living inside the human body. These circular genetic structures, termed obelisks, differ from known viruses and bacteria and may represent a previously unclassified category of replicating RNA.
The findings emerged from a comprehensive analysis of genetic material drawn from human-associated microbial communities. Obelisks appear frequently in samples collected from the mouth and gut, among other locations, and may be present across global populations. Their exact function is still unclear.
What sets these RNA entities apart is their simplicity. They do not encode proteins, nor do they appear to form protective protein shells. Instead, they consist of short loops of RNA that replicate in ways that remain poorly understood.
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