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Tampered images may have led Alzheimer’s research to fraudulent conclusions

by: Belle Carter

 

One of the most prevalent research papers on Alzheimer’s is likely a result of fraud. Years of research and hundreds of millions of taxpayer dollars may have been wasted on findings based on falsehoods.

The 2006 study was published in Nature and was written by Sylvain Lesné from the University of Minnesota, Twin Cities (UMN). This study has dominated the scientific community as a basis for other research on Alzheimer’s and has been cited repeatedly.

It supports a controversial hypothesis about Alzheimer’s: the amyloid hypothesis. The hypothesis suggests that protein amyloid beta clumps, called plaques, are a primary cause of Alzheimer’s when it exists in brain tissue.

However, Vanderbilt University neuroscientist and physician Matthew Schrag noticed that the images didn’t exactly match up. It appears that the photos used to support the study were actually composites from various other experiments, pieced together to form a single image. The images did not even appear to be from the study at all.

 

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