Press "Enter" to skip to content

This Artificial Sweetener Is More Damaging to Human Health Than Aspartame

 

 

Story at a glance:

  • Neotame, an artificial sweetener that’s chemically similar to aspartame, may seriously damage the human intestine and overall gut health.
  • Not only did neotame cause cell death in intestinal cells but it also damaged bacteria commonly found in the gut.
  • Neotame causes healthy gut bacteria to become diseased and invade the gut wall, which could lead to irritable bowel syndrome and sepsis.
  • Previous research by the scientists found that other artificial sweeteners, including saccharin, sucralose and aspartame, may similarly harm the gut.
  • Artificial sweeteners are also linked to additional health risks, including increased risk of Type 2 diabetes, cardiovascular diseases, cancer, anxiety and mortality in adults.

Neotame, an artificial sweetener that’s chemically similar to aspartame, may seriously damage the human intestine and overall gut health.

Sometimes listed on food ingredient labels as E961, neotame is a relative newcomer to the artificial sweetener market, and despite well-known health concerns, is expected to reach a global market value of $3 billion by the end of 2025.

Neotame, developed in 2002 as an alternative to aspartame, is up to 13,000 times sweeter than sugar and is widely used in drinks, sauces, sweets, savory foods and chewing gum.

Yet, “Despite widespread global use of neotame, there are surprisingly few research studies on the biological and physiological effects of the sweetener,” researchers wrote in Frontiers in Nutrition.

The team, from Anglia Ruskin University in Cambridge, England, found neotame poses serious risks to gut health, including causing healthy gut bacteria to become diseased.

Neotame may damage gut microbes, leading to irritable bowel syndrome and sepsis

The in vitro study involved models of the intestinal lining (Caco-2 cells) and gut bacteria (Escherichia coli and Enterococcus faecalis) to examine the effects of neotame exposure. Not only did neotame cause cell death in intestinal cells but it also damaged bacteria commonly found in the gut.

The damage to the intestinal epithelium decreased when researchers reduced the expression of a specific taste receptor, T1R3, which suggests neotame’s impact might be linked to taste perception pathways.

As noted in an Anglia Ruskin University press release:

“The study is the first to show that neotame can cause previously healthy gut bacteria to become diseased and invade the gut wall — potentially leading to health issues including irritable bowel syndrome and sepsis — and also cause a breakdown of the epithelial barrier, which forms part of the gut wall.”

Neotame also disrupted the intestinal barrier, leading to increased leakage and decreased presence of claudin-3, a protein important for cell binding, again through a T1R3-dependent mechanism.

In experiments involving gut bacteria, neotame increased harmful biofilm formation, which further reduced the viability of the intestinal lining, and increased the ability of E. coli and E. faecalis to stick to and invade intestinal cells.

According to study author Havovi Chichger, associate professor in biomedical science at Anglia Ruskin University, “When bacteria form a biofilm, they cluster together as a protective mechanism which makes them more resistant to antibiotics. Our study also shows that neotame increases the ability of the E coli to invade and kill human gut cells.”

What’s more, even consuming small amounts of neotame could be toxic.

Chichger said:

“Even when we studied neotame at very low concentrations, 10 times lower than the acceptable daily intake, we saw the breakdown of the gut barrier and a shift in bacteria to a more damaging behavior, including increased invasion of healthy gut cells leading to cell death. This can be linked to issues such as irritable bowel diseases and sepsis…

READ FULL ARTICLE HERE… (childrenshealthdefense.org)

Live Stream + Chat (zutalk.com)

 


Home | Caravan to Midnight (zutalk.com)

We Need Your Help To Keep Caravan To Midnight Going,

Please Consider Donating To Help Keep Independent Media Independent

Be First to Comment

Leave a Reply

Your email address will not be published. Required fields are marked *

This site uses Akismet to reduce spam. Learn how your comment data is processed.

Breaking News: