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Increased Mortality in Cancer Related to SARS-CoV-2 Spike Protein mRNA Injections: Japan Study



No significant excess mortality was observed during the first year of the pandemic (2020). However, some excess cancer mortalities were observed in 2021 after mass vaccination with the first and second vaccine doses, and significant excess mortalities were observed for all cancers and some specific types of cancer (including ovarian cancer, leukemia, prostate cancer, lip/oral/pharyngeal cancer, pancreatic cancer, and breast cancer) after mass vaccination with the third dose in 2022. AMRs for the four cancers with the most deaths (lung, colorectal, stomach, and liver) showed a decreasing trend until the first year of the pandemic in 2020, but the rate of decrease slowed in 2021 and 2022. This study discusses possible explanations for these increases in age- adjusted cancer mortality rates.

By James Kions-Weiler – originally published on his Substack

A study by Gibo et al. (2024) entitled Increased Age-Adjusted Cancer Mortality After the Third mRNA-Lipid Nanoparticle Vaccine Dose During the COVID-19 Pandemic in Japan, provides an analysis of the impacts of the COVID-19 pandemic, particularly the vaccination efforts, on cancer mortality in Japan.

The study examines age-adjusted mortality rates (AMRs) for various types of cancer during the COVID-19 pandemic, specifically looking at changes following the administration of the third dose of mRNA-lipid Nanoparticle injections.

The authors reported a distinct temporal pattern in cancer mortality rates.

In 2020, there was no noticeable increase in cancer mortality, indicating that the initial phase of the pandemic did not significantly affect cancer death rates. However, following the rollout of the first and second doses of the COVID-19 vaccine in 2021, an increase in excess mortality for some cancer types was observed. This trend became more pronounced in 2022, after the administration of the third vaccine dose, where significant excess mortality was noted across all cancers, with particular increases in ovarian, leukemia, prostate, lip/oral/pharyngeal, pancreatic, and breast cancers.

The also study identified a slowdown in the decrease of age-adjusted mortality rates (AMRs) for the four most prevalent cancer deaths (lung, colorectal, stomach, and liver) in 2021 and 2022, suggesting a deceleration in the progress against these cancers during the later stages of the pandemic.

(Left Side) The blue line with markers shows the real number of deaths from cancer (adjusted for age) per 100,000 people. A dashed line shows what the authors predicted those numbers would look like based on past data. Dotted lines frame what would be considered normal fluctuations around that prediction.

(Right Side) The bottom axis shows each month of the pandemic years (2020, 2021, 2022). Years where deaths were unusually high are marked: yellow spots mean slightly higher than expected, and pink spots mean much higher than expected. The left vertical axis tells us how much higher the actual deaths were compared to the percentage expected. The right vertical axis shows the number of COVID-19 vaccinations and the deaths caused by COVID-19.

In the study figure, a vertical line shows when COVID-19 started affecting Japan. Until 2020, the number of deaths decreased, but then it stopped decreasing. In 2021, deaths were higher than what is considered normal, and in 2022, they were even higher, going beyond the highest expected limit.

Deaths were way higher than expected, first in August 2021, around the same time many people were getting their first or second vaccine shots, and then in May 2022, after a lot of people received their third shot.

By Cancer Type in Detail

The study found that in 2020, only deaths from pancreatic cancer were slightly higher than what was normally expected. But as the years went on during the pandemic, more types of cancer showed unusually high death rates. In 2021, three out of twenty cancer types had higher deaths than expected, and by 2022, this number increased to five. The cancers with these higher death rates were ovarian cancer, leukemia, prostate cancer, lip/oral/pharyngeal cancer, and pancreatic cancer, with ovarian cancer showing the largest increase.

For ovarian cancer, the number of deaths was about 7.6% higher than expected in 2021 and increased to 9.7% higher in 2022. Leukemia, prostate cancer, lip/oral/pharyngeal cancer, and pancreatic cancer also saw increases, with leukemia deaths 8% higher than expected in 2022 and similar rises in the other types.

Interestingly, breast cancer showed a decrease in deaths compared to what was expected in 2020 and 2021. However, in 2022, there was a slight increase in breast cancer deaths, but this change was not large enough to be considered statistically significant. This means that while there was an uptick in breast cancer deaths in 2022, the numbers could still be due to random chance rather than a definitive increase.

Mechanisms Cited

The mechanisms cited in the study regarding the potential impacts of mRNA-LNP vaccines on cancer mortality and development are complex, citing various mechanisms of oncogenesis, many of which have been discussed here on Popular Rationalism many times before:

  • Vaccine Distribution and Molecular Concentration: Concentration: The authors report that the number of mRNA molecules per vaccine dose is extremely high, ranging into the trillions. According to the authors, there are only about 3 times more cells in the human body than LNPs. Once injected, these vaccines are distributed widely across the body, including critical organs like the liver and ovaries…


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